Webster's 1828 Dictionary
AN'TI-CHRIST, noun [Gr. against, and Christ.]
A great adversary of Christ; the man of sin; described
1 John 2:18. 2 Thessalonians 2:1. Revelation 9:1. Protestants generally suppose this adversary to be the Papal power; and some divines believe that, in a more general sense, the word extends to any persons who deny Christ or oppose the fundamental doctrines of christianity.