King James Bible Dictionary

lonesome that is (by implication) waste (usually as a noun G5561 being implied)

1. solitary, lonely, desolate, uninhabited

a. used of places

1. a desert, wilderness

2. deserted places, lonely regions

3. an uncultivated region fit for pasturage

b. used of persons

1. deserted by others

2. deprived of the aid and protection of others, especially of friends, acquaintances, kindred

3. bereft 1b

c. of a flock deserted by the shepherd 1b

d. of a woman neglected by her husband, from whom the husband withholds himself